Chickenpox (varicella)
This is highly contagious exanthematous illness caused by Varicella Zoster virus (herpes group)
Clinical features
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Incubation period is approx 15 days
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This starts with mild fever and constitutional features like body ache, runny nose
Skin features
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Centripetal distribution ( more over the chest/ back)
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Lesions occur as crops and appear simultaneously
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Lesions presents papules/ vesicles/ crusting
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Lesions can be itchy and painful
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The lesions erupt for about 5-7 days
Remember
Chickenpox is contagious about 2 days before onset of rash until crusting of them.
Never give salicylates in chickenpox as they can develop Reye’s syndrome
Lab tests
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Tzanck tests- the ruptures vesicles are fixed on a slide and stained to look for multinucleated giant cells
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Virus culture
Treatment
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Acyclovir is prescribed if nervous involvement, immunocompromised
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Itching can be treated with oral or intravenous antihistamine
Prevention
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Vaccination- 12 months of age onwards
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Passive immunity- immunoglobulin in immunocompromised, neonates whose mother developed varicella 5 days or less before birth